Table 1.
RA cercariae vaccine efficacy varies with host species and strain immune responses.
| RA vaccine | Host species and strain | Protection level | Immunity | References |
|---|---|---|---|---|
| S. mansoni | Mouse | C57BL/6 75–90% | Th1 and Th2 | [3,11,136] |
| S. mansoni | Mouse | BALB/c 30–60% | High DTH | [65] |
| S. mansoni | Mouse | CBA 4–66% | Low Ab levels | [136] |
| S. mansoni | Mouse | P/N | 10%-20% | Low DTH and Th1 [65,118] |
| S. mansoni | Baboons | 30–54% | High IgM/IgG | [17] |
| S. japonicum | Mouse | CBA/H 50–72% | High Ab levels | [109] |
| S. japonicum | Mouse | C57BL/6 2–40% | Low Th1 and Th2 | [32] |
DTH = delayed-type hypersensitivity; Ab = antibody.