Fig. 8.

Measurement of apoptosis induced by different concentrations of Isoniazid and combination of Isoniazid and ERK inhibitor in Hep3B cells by Annexin V FITC method. (A) Untreated Hep3B cells, (B) Hep3B cells treated with 50 µM ERK inhibitor, (C) Hep3B cells treated with 10 mM INH, (D) Hep3B cells treated with 20 mM INH, (E) Hep3B cells treated with combination of 50 µM ERK inhibitor and 10 mM INH, (F) Hep3B cells treated with combination of 50 µM ERK inhibitor and 20 mM INH. Experiments were performed in triplicate independently.