Table 2. Univariate Cox model for OS in the common cohort.
| Parameters | Risk group | HR | 95% CI | P-valuea |
|---|---|---|---|---|
| Age | — | 1.011 | 0.988–1.035 | 0.3444 |
| Smoking | Previous/current | 1.079 | 0.442–2.632 | 0.8672 |
| Histologyb | 0.0032 | |||
| Squamous | 1.852 | 0.776–4.422 | ||
| Other | 3.449 | 1.677–7.093 | ||
| Stage | IIIB-IV | 2.415 | 1.149–5.076 | 0.02 |
| Surgery | No | 2.132 | 0.980–4.637 | 0.0563 |
| Radiation therapy | No | 0.817 | 0.439–1.521 | 0.5236 |
| Chemotherapy | No | 0.956 | 0.438–2.085 | 0.9101 |
| LAMC2c | — | 1.578 | 1.207–2.063 | 0.0009 |
| CA 125c | — | 1.339 | 1.151–1.557 | 0.0002 |
| CEAc | — | 1.058 | 0.947–1.181 | 0.318 |
| CYFRA 21-1c | — | 1.492 | 1.239–1.798 | <0.0001 |
| SCCc | — | 1.040 | 0.741–1.461 | 0.8197 |
Abbreviations: CI=confidence interval; CA 125=cancer antigen 125; CEA=carcinoembryonic antigen; HR=hazards ratio; OS=overall survival; SCC=squamous cell carcinoma antigen.
a
Bold values are statistically significant (P<0.05).
b
Adenocarcinoma is the reference group (HR=1).
c
Markers were analysed as log transformed continuous variables.