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Histologic and inflammatory reaction in MSI tumours. (A) H&E stain shows that this tumour is composed of a glandular and solid pattern. (B, C) Histology of the glandular and solid pattern in more detail. (D, E) Immunohistochemistry for CD3 shows a combination of intratumoral and intraepithelial lymphocytes in the glandular part of the MSI tumour, while mainly intra-epithelial lymphocytes were found in the solid part of the MSI tumour.
