Table 2. Temporal trends in colorectal cancer presentation with the introduction of screening.
All patients |
Pre-screening |
Screening introduction |
Postscreening |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Early |
Late |
Early |
Late |
||||||||||
|
2003–2004 |
2005–2006 |
2007–2008 |
2009–2010 |
2011–2012 |
||||||||
n (14 487) | % | n (2380) | % | n (2384) | % | n (3098) | % | n (3282) | % | n (3343) | % | P-value | |
Age (years) | |||||||||||||
⩽50 | 751 | 5 | 129 | 5 | 129 | 5 | 172 | 6 | 139 | 4 | 182 | 5 | |
50–74 | 8142 | 56 | 1250 | 53 | 1368 | 57 | 1702 | 55 | 1897 | 58 | 1925 | 58 | |
⩾75 | 5299 | 37 | 851 | 35 | 793 | 33 | 1202 | 39 | 1224 | 37 | 1229 | 37 | 0.584 |
Unknown | 295 | 2 | 150 | 6 | 94 | 4 | 22 | 1 | 23 | 1 | 6 | 0 | |
Sex | |||||||||||||
Female | 6364 | 44 | 1017 | 42 | 1054 | 44 | 1384 | 45 | 1416 | 43 | 1493 | 45 | |
Male | 7827 | 54 | 1213 | 51 | 1236 | 52 | 1692 | 55 | 1843 | 56 | 1843 | 55 | 0.169 |
Unknown | 296 | 2 | 150 | 6 | 94 | 4 | 22 | 1 | 23 | 1 | 7 | 0 | |
Deprivation category | |||||||||||||
1 (most deprived) | 4329 | 30 | 667 | 28 | 706 | 30 | 935 | 30 | 978 | 30 | 1043 | 31 | |
2 | 3398 | 23 | 545 | 23 | 555 | 23 | 732 | 24 | 776 | 24 | 790 | 24 | |
3 | 2370 | 16 | 364 | 15 | 380 | 16 | 529 | 17 | 557 | 17 | 540 | 16 | |
4 | 1921 | 13 | 307 | 13 | 300 | 13 | 406 | 13 | 433 | 13 | 475 | 14 | |
5 (least deprived) | 2072 | 14 | 247 | 16 | 349 | 15 | 474 | 15 | 514 | 16 | 488 | 15 | 0.057 |
Unknown | 297 | 2 | 150 | 6 | 94 | 4 | 22 | 1 | 24 | 1 | 7 | 0 | |
Presentation to surgery | |||||||||||||
Emergency | 2163 | 15 | 480 | 20 | 431 | 18 | 414 | 13 | 420 | 13 | 418 | 13 | |
Elective | |||||||||||||
Symptomatic | 8948 | 62 | 1849 | 78 | 1868 | 78 | 1910 | 62 | 1729 | 53 | 1592 | 47 | |
Screen detecteda | 1200 | 8 | — | — | — | — | 107 | 3 | 486 | 15 | 607 | 18 | ⩽0.001b |
Did not undergo procedure | 2056 | 14 | 30 | 1 | 56 | 2 | 624 | 20 | 642 | 20 | 704 | 21 | |
Unknown | 115 | 1 | 21 | 5 | 29 | 3 | 43 | 1 | 5 | 0 | 22 | 1 | |
Site of tumour | |||||||||||||
Right colon | 4857 | 34 | 753 | 32 | 811 | 34 | 1048 | 34 | 1099 | 34 | 1146 | 34 | |
Left colon | 4827 | 33 | 790 | 33 | 736 | 31 | 997 | 32 | 1165 | 35 | 1139 | 34 | |
Rectum | 4647 | 32 | 825 | 34 | 818 | 34 | 996 | 32 | 983 | 30 | 1025 | 31 | 0.001 |
Multiple/unknown | 156 | 1 | 12 | 1 | 19 | 1 | 57 | 2 | 35 | 1 | 33 | 1 | |
Management Intent | |||||||||||||
Curative intent | 9980 | 68 | 1797 | 76 | 1744 | 73 | 1972 | 64 | 2238 | 68 | 2229 | 67 | |
Palliative procedure | 1877 | 13 | 440 | 18 | 389 | 16 | 337 | 11 | 334 | 10 | 377 | 11 | ⩽0.001c |
Did not undergo procedure | 2056 | 14 | 30 | 1 | 56 | 2 | 624 | 20 | 642 | 20 | 704 | 21 | |
Unknown/other | 574 | 4 | 113 | 5 | 195 | 8 | 165 | 5 | 68 | 2 | 33 | 1 |
Recorded from 2007 onwards.
Emergency vs all elective (including screen detected).
Curative vs palliative resection.