Table 1B. Univariate and multivariate Cox proportional hazards regression model for progression-free survival (n=140).
Variables | Univariate P-value | HR (95% CI) | Multivariate P-value | HR (95% CI) |
---|---|---|---|---|
Age | 0.013 | 1.023 (1.005–1.042) | 0.875 | |
Optimal cytoreductive surgery | <0.001 | 3.55 (2.15–5.86) | 0.005 | 2.10 (1.25–3.52) |
Stage III/IV vs I/II | <0.001 | 8.11 (4.33–15.19) | <0.001 | 7.17 (3.79–13.58) |
IMP1 | 0.92 | 0.97 (0.63–1.51) | ||
IMP2 | 0.61 | 1.11 (0.72–1.74) | ||
IMP3 | 0.015 | 1.73 (1.10–2.71) | 0.05 | 1.57 (1.01–2.48) |
Lin28B | 0.007 | 1.84 (1.18–2.86) | 0.08 | |
Lin28 | 0.23 | 0.76 (0.48–1.18) |
Abbreviation: CI=confidence interval; HR=hazard ratio; IMP=insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs; refered to as IMPs).