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. 2015 Jul 9;113(3):414–424. doi: 10.1038/bjc.2015.254

Table 1B. Univariate and multivariate Cox proportional hazards regression model for progression-free survival (n=140).

Variables Univariate P-value HR (95% CI) Multivariate P-value HR (95% CI)
Age 0.013 1.023 (1.005–1.042) 0.875  
Optimal cytoreductive surgery <0.001 3.55 (2.15–5.86) 0.005 2.10 (1.25–3.52)
Stage III/IV vs I/II <0.001 8.11 (4.33–15.19) <0.001 7.17 (3.79–13.58)
IMP1 0.92 0.97 (0.63–1.51)    
IMP2 0.61 1.11 (0.72–1.74)    
IMP3 0.015 1.73 (1.10–2.71) 0.05 1.57 (1.01–2.48)
Lin28B 0.007 1.84 (1.18–2.86) 0.08  
Lin28 0.23 0.76 (0.48–1.18)    

Abbreviation: CI=confidence interval; HR=hazard ratio; IMP=insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs; refered to as IMPs).