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. 2015 Aug 3;5:12645. doi: 10.1038/srep12645

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(A) Control measurement in ventricular cultures without CoCl₂ pre-treatment, showing no changes in fluorescence by medium change (MC). (B) In CoCl₂-pretreated ventricular cultures, reoxygenation through medium change (MC) causes a significant calcium increase in hypoxic ventricular cells. (C) In CoCl₂-pretreated ventricular cultures, administration of 0.5 μM KB-R7943 (ncx) reduced the calcium influx caused by reoxygenation. (D) In CoCl₂-pretreated ventricular cultures, administration of 1 μM KB-R7943 (NCX) eliminates the calcium influx caused by reoxygenation.