Table 4. Multivariate Cox proportional hazards regression of survival for the EORTC cohort (53 patients).
| Covariate | HR | 95% CI of HR | P-value |
|---|---|---|---|
| iCG + vs. - | 3.35 | (1.45, 7.70) | 4.5 × 10−3 |
| Age (per year) | 1.04 | (0.99, 1.10) | 1.0 × 10−1 |
| Gender male vs. female | 1.07 | (0.48, 2.37) | 8.7 × 10−1 |
| Type of surgery | 0.46 | (0.26, 0.83) | 9.4 × 10−3 |
| Performance status (0, 1, or 2) | 1.49 | (0.93, 2.40) | 9.8 × 10−2 |
| 1p/19q LOH + vs. - | 0.48 | (0.13, 1.79) | 2.8 × 10−1 |
| EGFR amplification + vs. - | 0.94 | (0.41, 2.12) | 8.8 × 10−1 |
| IDH1 mutation + vs. - | 0.41 | (0.17, 0.98) | 4.6 × 10−2 |
| MGMT methylation + vs. - | 2.65 | (0.89, 7.89) | 7.9 × 10−2 |
| Histology AOA vs. AOD | 2.31 | (1.05, 5.09) | 3.8 × 10−2 |
Note – HR: hazard ratio; CI: confidence interval.