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. 2015 Jul 30;6:7896. doi: 10.1038/ncomms8896

Figure 3. Paromomycin effects on intersubunit rotation in wild-type and A1408G aminoglycoside-resistant ribosomes.

Figure 3

(a,b) (Top panels) smFRET trajectories summed into FRET histograms reveal the population behaviours across a range of paromomycin concentrations in (a) wild-type and (b) A1408G ribosomes. (Bottom panels) Initial and final FRET values for each transition summed into two-dimensional histograms (transition density plots). Experiments were performed in triplicate on three separate days.