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. 2015 Jul 30;6:7858. doi: 10.1038/ncomms8858

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(a,b) Confocal z-stack projection of activated grid vessels perfused with whole blood without (a) or with (b) the GPIbα blocker AK2: merged (left panel), platelets (middle panel) and platelets-VWF (right panel). Red: CD31, green: VWF, magenta: CD41a and blue: nuclei. Scale bar: 100 μm. (c) 3D reconstructed image of an activated grid vessel near the outlet after 15 min of perfusion of whole blood containing AK2. Red: CD31, green: VWF and blue: nuclei. (d) Vessel wall surface area covered by adherent platelets after 15 min of blood perfusion in the presence of either control mIgG or AK2. Error bar: s.d. **P<0.01 with student's t-test. Three replicates were done. N >3.