Fig. 3.

(A) Contact angles of aqueous solutions of osmolytes on polystyrene and (B) polystyrene–liquid interfacial tensions, as calculated using pendant drop and contact angle measurements. Preferential binding coefficients ($\mathrm{\Gamma }$) as a function of distance to PS₂₀ for TMAO (C) and urea (D), as obtained from MD simulations, are plotted for three different polymer conformations (collapsed, red; intermediate, black; extended, green).