Fig. 4.

Direct contact between tangentially migrating neuroblasts and blood vessels in the adult dentate gyrus. (A) (Left) Quantification of the distribution of various labeled precursors in close association with the vasculature at 7 dpi. Values represent mean ± SEM. (Right) Summaries of precursor cell molecular marker expression and the percentage of a given cell subtype in close association with the vasculature. BV, blood vessel. (B) Three-dimensional reconstruction, from serial electron microscopic sections, of a GFP⁺ SGZ neuronal precursor (NP1; closed arrowhead) extending a tangential process along a blood vessel. The immunofluorescence-identified, immunoperoxidase-labeled cell (Top) sits alongside another neuronal precursor (NP2; open arrowhead) and apposes the blood vessel with both its tangential process (Middle Left) and its cell body (Top Right; arrowhead). (Scale bars, 5 µm.)