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. 2015 Jul 13;112(30):E4085–E4093. doi: 10.1073/pnas.1417222112

Fig. 6.

Fig. 6.

Genetic studies in humans. (A) Whole-brain analysis of reward anticipation large win vs. no win during the MID task shows positive BOLD response (PBR) during reward anticipation (family-wise error P < 0.05). The location of the VS (±15, 9, −9; 9-mm radius) is depicted in blue. The results of association analyses between VS and RSU1 gene are summarized. ROI, region of interest. (B) Exon/intron schematic of the RSU1 gene. The first SNP of haplotype block 6 (rs7921941; red), the last SNP of haplotype block 5 (rs12572686; green), and the main SNP (rs7078011; asterisk and blue) are highlighted. The eighth exon is indicated with an arrow. (C) Summary of genetic analyses of alcohol drinking in the human datasets IMAGEN, SAGE, and NFBC1966.