Fig. S6.
Ligand-binding sites of the nsp14 N7-MTase domain. Substrates SAM (A) and GpppA and SAH (B) bind in pockets formed by the β1-sheet, β2-sheet, and α1′. Fo-Fc electron density maps (omit map) for SAM, GpppA, and SAH contoured at 2σ are shown.
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