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. Author manuscript; available in PMC: 2015 Aug 3.
Published in final edited form as: Genet Med. 2014 Jun 19;17(1):43–50. doi: 10.1038/gim.2014.68

Table 1.

Personal and family cancer history features used to assign participants to high- or elevated-risk categories

Categorya High risk Elevated risk
Non-Jewish

  • 2 FD relatives with br ca, 1 dx ≤ age 50

  • 3 Or more FD and/or SD relatives with br ca dx at any age

  • 1 FD relative with bilateral br ca

  • 1 FD or SD relative with both br ca and ov ca

  • 1 FD or SD male relative with br ca

  • Personal hx br ca dx ≤ age 50

  • 2 FD and/or SD relatives with ov ca

  • 1 FD and 1 SD relative with br ca dx ≤ age 50

  • 2 Paternal SD relatives with br ca dx ≤ age 50

  • 1 FD relative with ov ca

  • 2 Maternal SD relatives with br ca dx ≤ age 50

  • Personal hx br ca dx > age 50

  • 2 SD relatives with br ca dx > age 50

  • 1 FD and 1 SD relative with br ca, 1 dx ≤ age 50

  • 1 FD relative with br ca dx ≤ age 50
Jewish

  • 1 FD relative with br ca

  • 1 SD relative with br ca dx ≤ age 50

  • 1 FD or SD relative with ov ca

  • 2 SD relatives with br ca or 1 with br ca and 1 with ov ca

  • FD or SD male relative with br ca

  • Personal hx br ca dx any age

  • 1 SD relative with br ca dx > age 50

Personal history of ovarian cancer was not included because those with a previous diagnosis were not eligible for the study. If two SD relatives were involved, they had to be from the same side of the family.

br ca, breast cancer; dx, diagnosed; FD, first degree; hx, history; ov ca, ovarian cancer; SD, second degree.

a

All other respondents were classified as “average risk.”