Table 4.
Adjusted odds ratios and 95% CIs for genetic counseling referral and BRCA1/2 testing
| Participant characteristic |
Referred for genetic counseling (n = 212) |
Had BRCA1/2 testing (n = 92) |
|---|---|---|
| OR (95% CI) | ||
| Age (years) | ||
| <40 | 1.00 | 1.0 |
| 41–50 | 0.61 (0.31–1.23) | 1.30 (0.34–4.86) |
| 51–60 | 0.80 (0.37–1.76) | 1.13 (0.29–4.30) |
| 61–64 | 0.67 (0.26–1.73) | 0.82 (0.23–2.90) |
| ≥65 | 0.53 (0.21–1.35) | 2.50 (0.48–13.13) |
|
| ||
| Race | ||
| White | 1.00 | 1.00 |
| Black | 1.07 (0.63–1.81) | 1.36 (0.57–3.25) |
| Other | 1.92 (0.84–4.41) | 0.55 (0.29–1.03) |
|
| ||
| Marital status | ||
| Married/partnered | 1.00 | 1.00 |
| Divorced/separated | 0.79 (0.46–1.37) | 1.18 (0.52–2.69) |
| Single/never married | 0.92 (0.48–1.78) | 0.17 (0.07–0.44) |
| Widowed | 2.02 (0.84–4.87) | 1.58 (0.44–5.92) |
|
| ||
| Education level | ||
| ≤High school/GED | 1.00 | 1.00 |
| College, <4 years | 0.87 (0.49–1.53) | 1.27 (0.39–4.20) |
| College, undergraduate degree |
0.65 (0.37–1.15) | 1.87 (0.40–8.68) |
| Graduate degree | 2.08 (1.04–4.14) | 1.87 (0.44–7.90) |
|
| ||
| Annual income ($) | ||
| <35,000 | 1.00 | 1.0 |
| 35,000–<50,000 | 0.99 (0.50–1.98) | 0.24 (0.10–0.62) |
| 50,000–<75,000 | 1.00 (0.47–2.12) | 0.43 (0.17–1.08) |
| ≥75,000 | 1.17 (0.58–2.34) | 0.48 (0.12–1.81) |
|
| ||
| Parity | ||
| No | 1.00 | 1.00 |
| Yes | 0.73 (0.43–1.24) | 1.77 (0.49–6.82) |
|
| ||
| Assigned risk category | ||
| Average | 1.00 | 1.00 |
| Elevated | 2.23 (1.41–3.54) | 0.67 (0.28–1.63) |
| High | 5.74 (3.82–8.64) | 1.21 (0.53–2.74) |
|
| ||
| Personal history of breast cancer | ||
| No | 1.00 | 1.00 |
| Yes, diagnosed at age ≤ 50 years |
3.10 (2.27–4.22) | 8.05 (4.99–13.00) |
| Yes, diagnosed at age > 50 years |
3.12 (2.12–5.32) | 5.33 (2.20–9.64) |
|
| ||
| Perceived 10-year risk of ovarian cancer | ||
| Lower | 1.00 | 1.00 |
| Same | 1.01 (0.59–1.76) | 1.32 (0.48–3.62) |
| Higher | 2.14 (1.34–3.43) | 2.93 (0.92–9.32) |
|
| ||
| Perceived influence of family history on cancer risk | ||
| Decreases | 1.00 | 1.00 |
| No effect | 1.47 (0.68–3.17) | 4.61 (2.20–9.64) |
| Increases | 1.00 (0.50–2.01) | 10.44 (3.89–27.99) |
|
| ||
| Talked to HCP about family cancer history | ||
| No | 1.00 | 1.00 |
| Yes | 2.40 (1.09–5.32) | 1.53 (0.48–4.83) |
|
| ||
| Referred for genetic counseling | ||
| No | — | 1.00 |
| Yes | — | 12.94 (7.96–21.04) |
Significant findings are displayed in bold. All variables are included in multivariable logistic regression model.
CI, confidence interval; GED, general educational development (high school equivalency); HCP, health-care provider; OR, odds ratio.