Table 2.

Estimated coefficients of the models and ANOVA analysis for the three disruption models in which the experimental results were fitted to the following equation:

$$Y_{\text{k}}={\mathrm{\beta }}_{\text{0,k}}+\sum {\mathrm{\beta }}_{\text{i,k}}\cdot X_{\text{i}}+\sum {\mathrm{\beta }}_{\text{ii,k}}\cdot X_{\text{i}}^2+\sum {\mathrm{\beta }}_{\text{ij,k}}\cdot X_{\text{i}}\cdot X_{\text{j}},$$

where, i = 1 for OD₀, i = 2 for N; k = 1 for ODD, k = 2 for TPR, and k = 3 for APAR.

	OD decrease ODD-model			Total protein released TPR-model			AP activity released APAR-model
	Coefficient	t-Value	p-Value	Coefficient	t-Value	p-Value	Coefficient	t-Value	p-Value
β0	51.05	22.97	<0.0001	−0.32	−0.05	0.9594	0.132	6.7717	0.0003
β1	−0.03	−0.61	0.5618	2.19	18.43	<0.0001	1.10E-03	2.9067	0.0228
β2	24.51	11.72	<0.0001	16.01	2.80	0.0266	0.081	4.4537	0.003
β11	0.00	3.54	0.0094	−0.02	−22.72	<0.0001	−7.63E-06	−2.8456	0.0248
β22	−3.76	−7.62	0.0001	−3.41	−2.53	0.039	−0.020	−4.558	0.0026
β12	−0.03	−3.29	0.0133	0.02	0.82	0.4408	9.88E-05	1.1063	0.3051
R2	0.9882			0.9900			0.9210
SEE (%)	0.99			3.32			2.86