Table 5.

Logistic regression models for BPD (5a) and severe BPD (5b) among Caucasian infants:

Variable	Odds ratio	95% CI	P - value
BPD
GA ≤ 26wk	3.2	1.8 – 5.7	<.0001
Birth weight ≤ 800g	2.7	1.4 – 5.2	0.002
Male gender	1.8	1.2 – 2.7	0.009
NQO1 TT vs. CC or CT	4.2	1.5 – 11.1	0.006
NFE2L2 CA or AA vs. CC	0.48	0.3 – 0.8	0.005
PDA	2.9	1.9 – 4.6	<.0001
Severe BPD
Gestational age ≤ 26wk	3.6	1.9 – 6.7	<.0001
Birth weight ≤ 800g	2.3	1.2 – 4.5	0.01
Male gender	1.9	1.1 – 3.2	0.02
NFE2L2 CA or AA vs. CC	0.3	0.1 – 0.6	0.0003
PDA	2.6	1.5 – 4.4	0.0004

Epidemiological variables available at birth, ARE variants and PDA were investigated with logistic regression to model BPD and severe BPD risk. Risk-factors that remained (p<0.05) associated with BPD and severe BPD are depicted.