Skip to main content
. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Food Chem Toxicol. 2015 Jan 5;77:34–43. doi: 10.1016/j.fct.2014.12.013

Fig. 2.

Fig. 2

Lico-A-induced FaDu cell death is mediated by both intrinsic and extrinsic apoptotic pathways. FaDu cells were treated with 50 and 100 µM Lico-A for 24 h. After treatment, both total protein and conditioned media were harvested FaDu cells and then western blots were performed. (A) Lico-A increases TRAIL expression in both cell lysate and conditioned media as a dose-dependent manner. (B) Lico-A induces the extrinsic apoptotic signaling pathway. (C) Lico-A induces the intrinsic apoptotic signaling pathway. (D) Lico-A induces FaDu cell death by activating caspase-3 and poly (ADP ribose) polymerase (PARP).