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. 2015 Aug 4;13:252. doi: 10.1186/s12967-015-0592-z

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© Zheng et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — PTEN expression is inversely related to that of miR-106b in colorectal cancer. a A western blot for the PTEN protein was performed in colorectal cancer cell lines. b qRT-PCR on 15 colorectal cancer patients. The association between miR-106b and PTEN mRNA for the 15 subjects in the tumour class and for the paired 15 subjects in the normal class was statistically calculated using the Spearman correlation coefficient (p = 0.006, Spearman’s r = −0.491). The Spearman correlation indicated an inverse relation between miR-106b and PTEN mRNA in the normal and tumour samples.