Table 2. Baseline Laboratory Characteristics, Site and Type of Infection, and Isolated Microbiological Agent in the General Population and in the Groups of Patients Who Survived or Died at 30-Day Follow-Up.
Overall population (n = 144) | Death at 30 days |
P | ||
---|---|---|---|---|
No (n = 103) | Yes (n = 41) | |||
Laboratory values | ||||
WBC count (1,000/mm3) | 10.4 ± 9.3 | 10.9 ± 8.4 | 11.1 ± 11.3 | 0.54 |
Hemoglobin (g/dL) | 10.7 ± 1.7 | 11.1 ± 2.2 | 10.7 ± 1.9 | 0.29 |
Platelet count (1,000/mm3) | 210 ± 143 | 204 ± 136 | 223 ± 159 | 0.47 |
Creatinine (mg/dL) | 1.7 ± 1.8 | 1.9 ± 1.7 | 1.3 ± 0.7 | 0.67 |
Lactate (mmol/L) | 2.3 ± 1.6 | 2.4 ± 1.9 | 2.1 ± 1.0 | 0.38 |
Cardiac troponin I (μg/L) | 0.3 ± 0.5 | 0.3 ± 0.6 | 0.1 ± 0.3 | 0.21 |
ProBNP (pg/mL) | 9,244 ± 14,805 | 9,613 ± 16,604 | 7,998 ± 7,301 | 0.66 |
PCT on admission (ng/mL) | 28.06 ± 63.29 | 34.1 ± 70.1 | 12.7 ± 33.7 | 0.07 |
PCT at 24 h (ng/mL) | 29.09 ± 63.28 | 33.64 ± 70.05 | 16.81 ± 37.87 | 0.19 |
PCT at 72 h (ng/mL) | 13.48 ± 29.04 | 13.31 ± 31.97 | 13.92 ± 20.21 | 0.91 |
Site and type of infection | ||||
Lung | 74 (51.4%) | 47 (45.6%) | 27 (65.9%) | 0.04 |
Urinary tract | 32 (22.2%) | 30 (29.1%) | 2 (4.9%) | 0.001 |
Gall bladder | 6 (4.2%) | 5 (4.9%) | 1 (2.4%) | 0.67 |
Other | 32 (22.2%) | 21 (20.4%) | 11 (26.8%) | 0.69 |
Septic shock | 51 (35.4%) | 25 (24.3%) | 26 (63.4%) | < 0.0001 |
Nosocomial | 33 (22.9%) | 21 (20.4%) | 12 (29.3%) | 0.27 |
Community acquired | 111 (77.1%) | 82 (79.6%) | 29 (70.7%) | 0.27 |
Isolated agent | ||||
Positive blood cultures | 67 (46.5%) | 49 (47.6%) | 18 (43.9%) | 0.42 |
Gram-positive | 27 (18.7%) | 17 (16.5%) | 10 (24.4%) | 0.26 |
Gram-negative | 30 (20.8%) | 24 (23.3%) | 6 (14.6%) | 0.15 |
Fungi | 3 (2.1%) | 2 (1.9%) | 1 (2.4%) | 0.77 |
Polymicrobial | 7 (4.9%) | 11 (10.7%) | 6 (14.6%) | 0.63 |
WBC: white blood cell count; ProBNP: pro-brain natriuretic peptide; PCT: procalcitonin.