FIG. 4.

Cerebral glycolysis assessed by ¹⁸F-labeled fluorodeoxyglucose (¹⁸F-FDG) positron emission tomography (PET)/CT imaging. (A) Representative ¹⁸F-FDG PET/CT images of sham, vehicle-treated, or E₂-SO₄-treated animals at 1 or 7 days after administration. The intensity of PET images is normalized to that of the central brain region. The area that underwent craniectomy is indicated with a yellow arrow in each figure part. (B) Mean relative standardized uptake value (SUV) (ratio of SUV of the upper half brain to that of central brain region) of sham, vehicle-treated, or E₂-SO₄-treated groups (n=5 per group) at 1 or 7 days after administration. Asterisk and hashtag represent statistical difference from sham and vehicle-treated groups, respectively. Color image is available online at www.liebertpub.com/neu