. Author manuscript; available in PMC: 2015 Aug 3.

Published in final edited form as: Epilepsy Behav. 2008 Oct 30;14(1):253–257. doi: 10.1016/j.yebeh.2008.09.007

Table 1.

Summary of EPC cases treated with rTMS in the Berenson-Allen Center for Noninvasive Brain Stimulation, and affiliated institutions.

Patient	Age (Years)	Etiology	Coil Position	rTMS Intensity	rTMS Frequency	Train Duration	# Trains	Outcome	Adverse Events
1	42	Hypoglycemia	Seizure Focus	100% MT	1 Hz	1800 sec	3	Clinical seizures stopped for 30 min after each train, then resumed	none
2	56	Stroke, Hypoglycemia	Seizure Focus	100% MT	1^st Session: 1 Hz 2^nd Session: 20 Hz, then 1 Hz,	20 Hz: 2 sec 1 Hz: 1600 sec	1^st Session: 1 (1 Hz) 2^nd Session: 40 at 20 Hz, then 1 at 1 Hz	1^st Session: No effect 2^nd Session: clinical seizures stopped for 20 min, then resumed
3	33	Unknown	Seizure Focus	100% MT	6 Hz then 1 Hz	6 Hz priming then 1 Hz for 1600 sec	2	1^st Session 1: Clinical seizures improved during rTMS 2^nd Session: Clinical seizures improved during stimulation, stopped for 20 minutes, then resumed	none
4	18	Unknown	Seizure Focus	100% MT	1 Hz	2000 sec	1	Clinical seizures stopped, and were absent for remainder of 2-day inpatient stay^*	none
5	46	Resected cortical vascular malformation	Seizure Focus	90–100% MO	100 Hz, 1 Hz	100 Hz: 0.05–1.25 sec 1 Hz: 1600–1800 sec	1^st Session: 15 at100 Hz^†, then 1 at1 Hz) 2^nd Session: 10 at 1 Hz, daily	1^st Session: Clinical seizures improved after stimulation, however resumed within 3 months 2^nd Session: Clinical seizures improved and were suppressed at last follow-up (>4 months after rTMS)	none
6 [1]	11	Rasmussen’s Encephalitis	Seizure Focus	100% MT	1 Hz	1800 sec	9, daily	Clinical and EEG seizures were improved during stimulation, but returned to baseline within 30 min after each daily session	none
7	79	Stroke	Seizure Focus	100% MT	20 Hz, 1 Hz	20 Hz: 4 sec 1Hz: 30 min	1^st session >20 (20 Hz) 2^nd Session 1 (1 Hz)	1^st session: No effect 2^nd Session: Clinical seizures involving face arm and leg improved slightly to involve arm and leg only^**	Scalp, arm and leg pain with 20 Hz

MO: machine output; MT: motor threshold;

^†

100 Hz trains were delivered at successively increasing durations ranging from 0.05 to 1.25 secs;

further follow-up is not available;

^**

patient sedated and intubated within one day of rTMS, thereafter lost to follow-up.