Table 1.
Morphologic types of metaplastic breast carcinomas analyzed in this study.
| Sample ID |
Diagnosis | Histologic gradea |
Triple- negative phenotypeb |
Metaplastic element present (diagnostic) | Matrix- producing |
Component in frozen sample |
|||
|---|---|---|---|---|---|---|---|---|---|
| Spindle | Squamous | Chondroid | Osseous | ||||||
| META33 | Carcinoma with mesenchymal elements | 3 | Yes | + | Chondroid | ||||
| META52 | Carcinoma with mesenchymal elements | 3 | Yes | + | + | Chondroid | |||
| META32 | Carcinoma with mesenchymal elements | 3 | Yes | + | + | Spindle | |||
| META39 | Carcinoma with mesenchymal elements | 3 | Yes | + | + | Spindle | |||
| META58 | Carcinoma with mesenchymal elements | 3 | Yes | + | + | Spindle | |||
| META59 | Carcinoma with mesenchymal elements | 3 | Yes | + | + | + | Spindle | ||
| META41 | Carcinoma with mesenchymal elements | 3 | Yes | + | + | Squamous | |||
| META43 | Carcinoma with mesenchymal elements | 3 | Yes | + | + | + | Squamous | ||
| META62 | Carcinoma with mesenchymal elements | 3 | Yes | + | + | + | Squamous | ||
| META30 | Carcinoma with mesenchymal elements | 3 | Yes | + | + | Chondroid | |||
| META31 | Carcinoma with mesenchymal elements | 2 | Yes | + | + | Chondroid | |||
| META53 | Carcinoma with mesenchymal elements | 3 | Yes | + | + | Chondroid | |||
| META64 | Carcinoma with mesenchymal elements | 3 | Yes | + | + | Chondroid | |||
| META36 | Carcinoma with mesenchymal elements | 2 | Yes | + | + | Chondroid | |||
| META55 | Carcinoma with mesenchymal elements | 3 | Yes | + | + | Chondroid | |||
| META44 | Carcinoma with mesenchymal elements | 3 | Yes | + | + | + | Squamous | ||
| META42 | Carcinoma with squamous metaplasia | 3 | Yes | + | Squamous | ||||
| META46 | Carcinoma with squamous metaplasia | 3 | Yes | + | Squamous | ||||
| META34 | Carcinoma with squamous metaplasia | 3 | Yes | + | Squamous | ||||
| META37 | Carcinoma with squamous metaplasia | 3 | Yes | + | + | Squamous | |||
| META47 | Spindle cell carcinoma | 3 | Yes | + | Spindle | ||||
| META49 | Spindle cell carcinoma | 3 | Yes | + | Spindle | ||||
| META56 | Spindle cell carcinoma | 3 | Yes | + | Spindle | ||||
| META57 | Spindle cell carcinoma | 3 | Yes | + | Spindle | ||||
| META60 | Spindle cell carcinoma | 3 | Yes | + | Spindle | ||||
| META65 | Spindle cell carcinoma | 3 | Yes | + | Spindle | ||||
| META45 | Spindle cell carcinoma | 3 | Yes | + | + | Squamous | |||
| META40 | Spindle cell carcinoma | 3 | Yes | + | + | Squamous | |||
+, present.
a
Histologic grading was performed according to Nottingham grading index.21
b
Triple-negative phenotype: lack of estrogen receptor, progesterone receptor, and HER2 expression.