Table 3.
Prevalences of use of each drug class according to the type of atrial fibrillation (AF) or flutter
| Drug | AF | Flutter(n = 51) | p value | |
|---|---|---|---|---|
| Paroxysmal (n = 188) | Persistent (n = 168) | |||
| Amiodarone | 25 (13.3) | 20 (11.9) | 9 (17.6) | 0.57 |
| Propafenone | 12 (6.4) | 5 (3) | 0 | 0.07 |
| Beta-blocker | 94(50) | 115 (68.9)* | 29 (56.9) | < 0.01 |
| Digoxin | 8 (4.3) | 38 (22.6)* | 8 (15.7)† | < 0.01 |
| CCB | 16 (8.5) | 32 (19.9)* | 3 (5.9) | 0.03 |
| Sotalol | 2 (1.1) | 3 (1.8) | 0 | 0.58 |
| Warfarin | 18 (9.6) | 47(28)† | 15 (29.4)† | < 0.01 |
| Phenprocoumon | 3 (1.6) | 12 (7.1)* | 4 (7.8) | 0.06 |
| Dabigatran | 6 (3.2) | 5 (3.0) | 0 | 0.44 |
| Rivaroxaban | 5 (2.7) | 3 (1.8) | 1 (2) | 0.82 |
| ACEi | 41 (21.8) | 70 (41.7)* | 16 (31.4) | < 0.01 |
| ARB | 31 (17) | 24 (14.3) | 4 (7.8) | 0.25 |
| Statins | 55 (29.3) | 50 (29.8) | 13 (25.5) | 0.83 |
| Diuretic | 47 (25) | 94 (56)* | 20 (39.2) | < 0.01 |
| Aspirin | 59 (31.4) | 62 (36.9) | 17 (33.3) | 0.54 |
| Clopidogrel | 13 (6.9) | 10 (6.0) | 1 (2.0) | 0.41 |
*
Difference between the groups with paroxysmal atrial fibrillation and persistent atrial fibrillation;
†
difference between the groups with flutter and paroxysmal atrial fibrillation. CCB: calcium channel blocker; ACEi: angiotensin-converting enzyme inhibitor; ARB: angiotensin receptor blocker.