Table 2.
Differentially expressed genes in erlotinib‐resistant (ER) HNSCC cells compared to erlotinib‐sensitive (ES) HNSCC cells.
| Gene symbol | Gene description | Fold change (ER vs ES) | |||
|---|---|---|---|---|---|
| FaDu | SQ20B | Cal‐27 | SCC‐25 | ||
| LCN2 | Neutrophil gelatinase associated lipocalin | 34.19 | 4.75 | 5.27 | 2.24 |
| CFB | Complement factor B | 20.78 | 6.64 | 7.00 | 2.07 |
| CYP1B1 | Cytochrome P450 1B1 | 19.06 | 6.14 | 3.05 | 4.98 |
| MUC1 | Mucin 1 | 6.81 | 2.09 | 2.12 | 3.98 |
| SASH1 | SAM and SH3 domain containing protein 1 | 6.44 | 4.81 | 3.18 | 2.63 |
| IL6 | Interleukin 6 | 4.92 | 6.08 | 4.82 | 2.26 |
| TIMP2 | Tissue inhibitor of metalloproteinase 2 | 3.95 | 2.95 | 2.06 | 2.35 |
| H19 | Long non‐coding RNA | 3.76 | −3.39 | −3.19 | 2.96 |
| ULBP1 | NKG2D ligand 1 | 2.48 | 6.95 | 3.08 | −2.09 |
| SLC1A4 | Neutral amino acid transporter A | 2.46 | 4.21 | 3.87 | −2.30 |
| PCK2 | Phosphoenolpyruvate carboxykinase 2 | 2.21 | 3.07 | 4.80 | −2.28 |
| FGFBP1 | Fibroblast growth factorbinding protein 1 | −2.93 | −11.63 | −2.32 | −2.75 |
| SFN | Stratifin | −3.51 | −2.51 | −3.28 | −2.08 |