Table 3.
Association between self-reported sleep and regional amyloid burden
ROI | Sleep Adequacy | Sleep Problems Index I | Somnolence | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
B | SE | t | p | η2p | B | SE | t | p | η2p | B | SE | t | p | η2p | ||
Angular Gyrus | L | −.002 | .001 | −1.948 | .055 | .041 | .002 | .002 | 1.409 | .162 | .022 | .003 | .002 | 2.282 | .025 | .055 |
R | −.003 | .001 | −2.910 | .005 | .087 | .004 | .002 | 2.299 | .024 | .056 | .004 | .001 | 2.461 | .016 | .064 | |
Cingulum Anterior | L | −.003 | .001 | −2.565 | .012 | .069 | .004 | .002 | 2.176 | .032 | .051 | .004 | .002 | 2.258 | .026 | .054 |
R | −.004 | .001 | −2.819 | .006 | .082 | .004 | .002 | 2.213 | .029 | .052 | .004 | .002 | 2.146 | .035 | .049 | |
Cingulum Posterior | L | −.003 | .001 | −2.536 | .013 | .067 | .004 | .002 | 2.155 | .034 | .050 | .002 | .002 | 1.300 | .197 | .019 |
R | −.002 | .001 | −2.373 | .020 | .059 | .003 | .002 | 2.113 | .037 | .048 | .002 | .001 | 1.291 | .200 | .018 | |
Frontal Med Orb | L | −.003 | .001 | −2.843 | .006 | .083 | .004 | .002 | 2.234 | .028 | .053 | .004 | .002 | 2.721 | .008 | .077 |
R | −.004 | .001 | −2.896 | .005 | .086 | .004 | .002 | 2.219 | .029 | .052 | .004 | .002 | 2.196 | .031 | .051 | |
Precuneus | L | −.003 | .001 | −2.461 | .016 | .064 | .004 | .002 | 2.154 | .034 | .050 | .003 | .002 | 2.090 | .040 | .047 |
R | −.003 | .001 | −2.823 | .006 | .082 | .004 | .002 | 2.331 | .022 | .058 | .003 | .002 | 2.020 | .046 | .044 | |
Supra-marginal | L | −.001 | .001 | −1.472 | .144 | .024 | .002 | .001 | 1.180 | .241 | .015 | .003 | .001 | 2.246 | .027 | .054 |
R | −.002 | .001 | −2.473 | .015 | .064 | .003 | .001 | 1.856 | .067 | .037 | .003 | .001 | 2.080 | .040 | .046 | |
Temporal Mid | L | −.001 | .001 | −1.542 | .127 | .026 | .001 | .001 | 1.068 | .288 | .013 | .002 | .001 | 2.006 | .048 | .043 |
R | −.002 | .001 | −2.067 | .042 | .046 | .002 | .002 | 1.353 | .180 | .020 | .002 | .001 | 1.711 | .090 | .032 | |
Temporal Sup | L | −.001 | .001 | −.830 | .409 | .008 | .001 | .001 | .676 | .501 | .005 | .002 | .001 | 1.864 | .066 | .038 |
R | −.002 | .001 | −1.998 | .049 | .043 | .002 | .001 | 1.277 | .205 | .018 | .002 | .001 | 1.663 | .100 | .030 | |
Mean | −.002 | .001 | −2.503 | .014 | .066 | .003 | .002 | 1.973 | .052 | .042 | .003 | .001 | 2.171 | .033 | .050 |
ROI, regions of interest; B, unstandardized regression coefficient; SE, standard error of the coefficient; p, p-value; η2p, partial eta squared. All models were adjusted for age, sex, APOE4, Family history of Alzheimer’s disease and body mass index. Statistically significant associations in bold, trends in italics.