Table 3. Pathological features of liver between groups at week 16.

1) Results for steatosis are means ± SD.
MF, Moderate-fat; HF, High-fat; HS, High-sucrose; HFr, High-fructose. "a,b,c,d," refer to differences between groups (P < 0.05). Small "a" refers to the MF group, small "b" refers to the HF group, small "c" refers to HS group, small "d" refers to the HFr group.
2) Results for macrovacuolar and microvesicular steatosis are given as number of rats presenting mild + (<33% of hepatocytes), moderate++ (33-66% of hepatocytes) or severe +++ (>66% of hepatocytes).
3) Necroinflammation and fibrosis are given as number of rats presenting a score of 0, 1 or 2 respectively.
4) Results for NAS are given as number of rats presenting scores of 0-2, 3-4 or 5-8 respectively. NAS, Non alcoholic fatty liver disease activity score.