Table 3.
Logistic modeling of factors associated with HO reexcision with included timing of excision occurring before or after 180 days after injury
| Variable | Coefficient | SE | OR (95% CI) | p value |
|---|---|---|---|---|
| CNS injury | 1.89 | 1.39 | 6.6 (0.72–883) | 0.11 |
| Complete versus partial excision | 1.61 | 0.74 | 5.0 (1.17–29.6) | 0.03* |
| HO severity (WR classification) | 0.09 | 0.45 | 1.10 (0.43–2.9) | 0.83 |
| Excision done < 180 days | 1.40 | 0.68 | 4.07 (1.02–16.6) | 0.047* |
| Surgeon experience | 1.06 | 0.69 | 2.88 (0.69–11.8) | 0.14 |
| Postexcision prophylaxis (NSAIDs) | −1.72 | 2.10 | 0.17 (0.003–4.4) | 0.32 |
| Postexcision prophylaxis (XRT) | 0.68 | 0.67 | 1.96 (0.51–8.8) | 0.33 |
* Statistically significant difference; HO = heterotopic ossification; OR = odds ratio; CI = confidence interval; CNS = central nervous system; WR = Walter Reed; NSAIDs = nonsteroidal antiinflammatory drugs; XRT = external beam radiation.