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Signal and additive noise levels for the four data scenarios considered
| Scenario | Mean number of single molecule photons N | Mean number of background photons per pixel | Mean of readout noise (e−/pixel) | Std. dev. of readout noise (e−/pixel) |
|---|---|---|---|---|
| 1 | 3000 | 0 | 0 | 0 |
| 2 | 3000 | 50 | 0 | 2 |
| 3 | 300 | 0 | 0 | 0 |
| 4 | 300 | 100 | 0 | 6 |
