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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Br J Ophthalmol. 2014 Jul 17;99(5):599–603. doi: 10.1136/bjophthalmol-2014-305550

Figure 1.

Figure 1

Schematic representation of an ideal surrogate endpoint. In this case, all mechanisms of action to the true endpoint are mediated through the surrogate endpoint.