Table 1.
Demographic and clinical characteristics.
| Healthy Controls | Remitted MDD | Acute MDD | HC vs. Rem MDD | HC vs. Acute MDD | Overall | |
|---|---|---|---|---|---|---|
| (n = 52) | (n = 66) | (n = 42) | p-valuesb | p-valuesb | p-valuesa | |
| Age (mean ± SD) | 28.3 ± 16.7 | 35.4 ± 17.1 | 37.4 ± 17.4 | 0.07 | 0.04 | 0.02 |
| Gender (n, %) | ||||||
| Females | 26 (50.0) | 39 (59.1) | 30 (71.4) | NA | NA | 0.10 |
| Years of education (mean ± SD) | 13.1±1.9 | 13.3±1.9 | 12.9±1.9 | 0.67 | 0.79 | 0.44 |
| Family history of major depressive disorder (n, %) | ||||||
| Yes | 13 (25.0) | 41 (62.1) | 26 (61.9) | NA | NA | < 0.001 |
| Currently using psychotropic medication (n, %) | ||||||
| Yes | 0 (0.0) | 23 (34.9) | 26 (61.9) | NA | NA | < 0.001 |
| SIGH-AD (mean ± SD) | ||||||
| Depression | 3.5 ± 2.9 | 9.8 ± 5.7 | 18.3 ± 6.5 | < 0.001 | < 0.001 | < 0.001b |
| Anxiety | 2.8 ± 2.6 | 9.6 ± 5.9 | 17.4 ± 7.5 | < 0.001 | < 0.001 | < 0.001b |
| Total | 6.3 ± 5.2 | 19.3 ± 11.1 | 35.8 ± 13.1 | < 0.001 | < 0.001 | < 0.001b |
a
P-values obtained from One-Way ANOVAs for continuous variables and Chi-Square test for binary variables.
b
Scheffe's post-hoc test.