Table 1.

Numbers of genes in the primary predicted host–fungal PPI networks belonging to the cellular component GO filter terms.

(A) Filter terms for host side
GO slim cellular component terms	Number of genes in Homo sapiens	Number of genes in Mus musculus
Extracellular region	2,566	783
Plasma membrane	2,310	2,024
Extracellular space	631	419
Endosome	476	421
Lysosome	306	247
Cilium	138	202
Proteinaceous extracellular matrix	115	132
External encapsulating structure	3	5
Only other GO terms	6,531	7,645
No GO terms	902	361
(B) Filter terms for fungi side
GO slim cellular component terms	Number of genes in Aspergillus fumigatus	Number of genes in Candida albicans
Plasma membrane	270	236
Extracellular region	94	33
Cell wall	52	74
Only other GO terms	3214	3160
No GO terms	0	1114
(C) Sizes of host–fungi PPI networks after localization refinement
Host species	Pathogen species	Number of host–pathogen interactions	Number of host interactors	Number of pathogen interactors
H. sapiens	A. fumigatus	17,853 (8.4%)	363 (10.2%)	2,393 (21.2%)
H. sapiens	C. albicans	15,330 (4.3%)	301 (6.6%)	2,123 (19.2%)
M. musculus	A. fumigatus	9,284 (4.5%)	337 (9.4%)	1,572 (14.9%)
M. musculus	C. albicans	8,055 (2.4%)	282 (6.2%)	1,376 (13.3%)