Figure 7. Loss of N-myc in GCPs disrupts the Shh signalling pathway and cyclin expression.
(A) The expression level of Shh signalling pathway upstream members in tTS mice and TRE mice. (B) The expression level of cyclin family members in the GCPs of tTS mice and TRE mice. (C) Western blotting assay of Ccnd2 expression in the GCPs of tTS mice and TRE mice. (D) Western blotting quantification of Ccnd2 expression. The assay was independently repeated three times. *p < 0.05.