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. 2012 Jul 9;17(7):8241–8254. doi: 10.3390/molecules17078241

Table 1.

If characteristics,* p < 0.05 vs. control, #p < 0.05 vs. ivabradine 3 μM.

Control Ivabradine Ivabradine Ivabradine
3 μM 10 μM 30 μM
(n = 9) (n = 9) (n = 9)
V1/2 activation (mV) −68 ± 4 −70 ± 4 −74 ± 4 * −77 ± 5 *
(p = 0.07) (p = 0.02) (p = 0.04)
Max τact 157 ± 11 120 ± 17 106 ± 17 * 80 ± 13 *
(ms) (P = 0.5) (P = 0.05) (P = 0.02)
If density (pA/pF) 4.5 ± 0.7 2.1 ± 0.3 * 1.6 ± 0.2 * 1.1 ± 0.2 *,#
(V = control V1/2 activation) (P = 0.04) (P = 0.008) (0.004)
If (pA/pF) (V = MDP) 3 ± 0.43 2 ± 0.3 * 1.5 ± 0.2 * 1.3 ± 0.2 *
(P = 0.045) (P = 0.04) (P = 0.01)