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. Author manuscript; available in PMC: 2015 Aug 4.
Published in final edited form as: Exp Clin Psychopharmacol. 2015 Aug;23(4):197–205. doi: 10.1037/pha0000026

Table 1.

Mean (±SEM) levels of DOPAC, 5-HIAA, DA and 5-HT from Experiments 4 and 5, expressed as µg/g wet weight tissue.

DOPAC
Experiment 4 Experiment 5
Male Female Male Female
Saline AMPH Saline AMPH Alone Social Int. Alone Social Int.
Region Mean (±SEM) Mean (±SEM) Mean (±SEM) Mean (±SEM) Mean (±SEM) Mean (±SEM) Mean (±SEM) Mean (±SEM)
Nacc 0.96 (±0.07) 0.91 (±0.10) 1.13 (±0.12) 0.85 (±0.09) 0.91 (±0.07) 0.82 (±0.09) 0.54 (±0.04) 0.65 (±0.07)
Str 1.62 (±0.32) 1.47 (±0.23) 1.49 (±0.24) 1.21 (±0.16) 0.98 (±0.11) 0.83 (±0.06) 0.73 (±0.04) 1.05 (±0.07)*
mPFC 0.04 (±0.00) 0.04 (±0.00) 0.05 (±0.01) 0.03 (±0.00) 0.02 (±0.00) 0.03 (±0.00) 0.02 (±0.00) 0.04 (±0.01)
Amyg 0.03 (±0.00) 0.02 (±0.00) 0.06 (±0.00) 0.02 (±0.00)* 0.03 (±0.00) 0.07 (±0.01)* 0.03 (±0.00) 0.05 (±0.00)
Hypo 0.11 (±0.03) 0.11 (±0.03) 0.13 (±0.02) 0.09 (±0.02) 0.04 (±0.00) 0.05 (±0.00) 0.07 (±0.00) 0.08 (±0.00)
MB 0.08 (±0.01) 0.06 (±0.00) 0.08 (±0.01) 0.08 (±0.00) 0.06 (±0.00) 0.06 (±0.00) 0.06 (±0.01) 0.06 (±0.00)
5-HIAA
Experiment 4 Experiment 5
Male Female Male Female
Saline AMPH Saline AMPH Alone Social Int. Alone Social Int.
Region Mean (±SEM) Mean (±SEM) Mean (±SEM) Mean (±SEM) Mean (±SEM) Mean (±SEM) Mean (±SEM) Mean (±SEM)
Nacc 0.56 (±0.04) 0.68 (±0.08) 0.50 (±0.07) 0.71 (±0.07) 0.45 (±0.02) 0.42 (±0.03) 0.25 (0.02) 0.31 (±0.02)
Str 0.53 (±0.04) 0.62 (±0.07) 0.63 (±0.50) 0.63 (±0.04) 0.33 (±0.01) 0.40 (±0.02)* 0.28 (±0.02) 0.42 (±0.03)*
mPFC 0.31 (±0.04) 0.26 (±0.05) 0.39 (±0.05) 0.35 (±0.04) 0.17 (±0.01) 0.19 (±0.02) 0.18 (±0.01) 0.24 (±0.02)*
Amyg 0.54 (±0.06) 0.41 (±0.07) 0.59 (±0.05) 0.51 (±0.06) 0.24 (±0.02) 0.21 (±0.01) 0.30 (±0.01) 0.33 (±0.00)*
Hypo 0.85 (±0.18) 0.87 (±0.17) 1.00 (±0.15) 0.86 (±0.14) 0.34 (±0.04) 0.42 (±0.01) 0.41 (±0.03) 0.5 (±0.02)
MB 1.13 (±0.17) 1.25 (±0.21) 1.17 (±0.16) 1.33 (±0.15) 0.70 (±0.02) 0.70 (±0.04) 0.72 (±0.03) 0.79 (±0.01)
DA
Experiment 4 Experiment 5
Male Female Male Female
Saline AMPH Saline AMPH Alone Social Int. Alone Social Int.
Region Mean (±SEM) Mean (±SEM) Mean (±SEM) Mean (±SEM) Mean (±SEM) Mean (±SEM) Mean (±SEM) Mean (±SEM)
Nacc 3.28 (±0.33) 3.94 (±0.33) 3.38 (±0.29) 4.03 (±0.25) 4.14 (±0.17) 3.23 (±0.42) 3.49 (±0.19) 3.41 (±0.24)
Str 0.44 (±0.18) 0.21 (±0.05) 0.36 (±0.10) 0.18 (±0.04) 4.36 (±0.38) 3.16 (±0.48) 3.62 (±0.34) 5.20 (±0.26)*
mPFC 0.04 (±0.00) 0.06 (±0.01) 0.04 (±0.00) 0.06 (±0.01) 0.04 (±0.00) 0.03 (±0.00) 0.05 (±0.01) 0.08 (±0.03)
Amyg 0.10 (±0.02) 0.08 (±0.01) 0.17 (±0.03) 0.11 (±0.02)* 0.13 (±0.01) 0.24 (±0.04) 0.14 (±0.01) 0.18 (±0.03)
Hypo 0.20 (±0.01) 0.25 (±0.01) 0.23 (±0.02) 0.19 (±0.02) 0.25 (±0.03) 0.24 (±0.02) 0.31 (±0.03) 0.33 (±0.02)
MB 0.28 (±0.03) 0.29 (±0.02) 0.28 (±0.04) 0.29 (±0.04) 0.25 (±0.01) 0.22 (±0.01) 0.26 (±0.01) 0.24 (±0.01)
5-HT
Experiment 4 Experiment 5
Male Female Male Female
Saline AMPH Saline AMPH Alone Social Int. Alone Social Int.
Region Mean (±SEM) Mean (±SEM) Mean (±SEM) Mean (±SEM) Mean (±SEM) Mean (±SEM) Mean (±SEM) Mean (±SEM)
Nacc 0.49 (±0.05) 0.52 (±0.05) 0.52 (±0.06) 0.60 (±0.07) 0.43 (±0.03) 0.35 (±0.02) 0.33 (±0.02) 0.36 (±0.02)
Str 0.24 (±0.01) 0.31 (±0.01) 0.31 (±0.02) 0.36 (±0.02) 0.18 (±0.01) 0.40 (±0.02)* 0.14 (±0.01) 0.21 (±0.02)*
mPFC 0.15 (±0.02) 0.16 (±0.02) 0.15 (±0.02) 0.23 (±0.03) 0.15 (±0.01) 0.15 (±0.01) 0.21 (±0.01) 0.19 (±0.01)
Amyg 0.53 (±0.04) 0.42 (±0.03) 0.62 (±0.09) 0.57 (±0.06) 0.28 (±0.04) 0.21 (±0.02) 0.48 (±0.01) 0.46 (±0.01)
Hypo 0.36 (±0.05) 0.42 (±0.02) 0.58 (±0.05) 0.67 (±0.04) 0.53 (±0.06) 0.67 (±0.08) 0.58 (±0.07) 0.61 (±0.09)
MB 0.64 (±0.02) 0.59 (±0.04) 0.70 (±0.03) 0.73 (±0.03) 0.59 (±0.05) 0.75 (±0.05) 0.68 (±0.08) 0.72 (±0.07)
*

p<0.05 compared to same-sex control group in that region.