Table 1.
DOPAC | ||||||||
Experiment 4 | Experiment 5 | |||||||
Male | Female | Male | Female | |||||
Saline | AMPH | Saline | AMPH | Alone | Social Int. | Alone | Social Int. | |
Region | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) |
Nacc | 0.96 (±0.07) | 0.91 (±0.10) | 1.13 (±0.12) | 0.85 (±0.09) | 0.91 (±0.07) | 0.82 (±0.09) | 0.54 (±0.04) | 0.65 (±0.07) |
Str | 1.62 (±0.32) | 1.47 (±0.23) | 1.49 (±0.24) | 1.21 (±0.16) | 0.98 (±0.11) | 0.83 (±0.06) | 0.73 (±0.04) | 1.05 (±0.07)* |
mPFC | 0.04 (±0.00) | 0.04 (±0.00) | 0.05 (±0.01) | 0.03 (±0.00) | 0.02 (±0.00) | 0.03 (±0.00) | 0.02 (±0.00) | 0.04 (±0.01) |
Amyg | 0.03 (±0.00) | 0.02 (±0.00) | 0.06 (±0.00) | 0.02 (±0.00)* | 0.03 (±0.00) | 0.07 (±0.01)* | 0.03 (±0.00) | 0.05 (±0.00) |
Hypo | 0.11 (±0.03) | 0.11 (±0.03) | 0.13 (±0.02) | 0.09 (±0.02) | 0.04 (±0.00) | 0.05 (±0.00) | 0.07 (±0.00) | 0.08 (±0.00) |
MB | 0.08 (±0.01) | 0.06 (±0.00) | 0.08 (±0.01) | 0.08 (±0.00) | 0.06 (±0.00) | 0.06 (±0.00) | 0.06 (±0.01) | 0.06 (±0.00) |
5-HIAA | ||||||||
Experiment 4 | Experiment 5 | |||||||
Male | Female | Male | Female | |||||
Saline | AMPH | Saline | AMPH | Alone | Social Int. | Alone | Social Int. | |
Region | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) |
Nacc | 0.56 (±0.04) | 0.68 (±0.08) | 0.50 (±0.07) | 0.71 (±0.07) | 0.45 (±0.02) | 0.42 (±0.03) | 0.25 (0.02) | 0.31 (±0.02) |
Str | 0.53 (±0.04) | 0.62 (±0.07) | 0.63 (±0.50) | 0.63 (±0.04) | 0.33 (±0.01) | 0.40 (±0.02)* | 0.28 (±0.02) | 0.42 (±0.03)* |
mPFC | 0.31 (±0.04) | 0.26 (±0.05) | 0.39 (±0.05) | 0.35 (±0.04) | 0.17 (±0.01) | 0.19 (±0.02) | 0.18 (±0.01) | 0.24 (±0.02)* |
Amyg | 0.54 (±0.06) | 0.41 (±0.07) | 0.59 (±0.05) | 0.51 (±0.06) | 0.24 (±0.02) | 0.21 (±0.01) | 0.30 (±0.01) | 0.33 (±0.00)* |
Hypo | 0.85 (±0.18) | 0.87 (±0.17) | 1.00 (±0.15) | 0.86 (±0.14) | 0.34 (±0.04) | 0.42 (±0.01) | 0.41 (±0.03) | 0.5 (±0.02) |
MB | 1.13 (±0.17) | 1.25 (±0.21) | 1.17 (±0.16) | 1.33 (±0.15) | 0.70 (±0.02) | 0.70 (±0.04) | 0.72 (±0.03) | 0.79 (±0.01) |
DA | ||||||||
Experiment 4 | Experiment 5 | |||||||
Male | Female | Male | Female | |||||
Saline | AMPH | Saline | AMPH | Alone | Social Int. | Alone | Social Int. | |
Region | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) |
Nacc | 3.28 (±0.33) | 3.94 (±0.33) | 3.38 (±0.29) | 4.03 (±0.25) | 4.14 (±0.17) | 3.23 (±0.42) | 3.49 (±0.19) | 3.41 (±0.24) |
Str | 0.44 (±0.18) | 0.21 (±0.05) | 0.36 (±0.10) | 0.18 (±0.04) | 4.36 (±0.38) | 3.16 (±0.48) | 3.62 (±0.34) | 5.20 (±0.26)* |
mPFC | 0.04 (±0.00) | 0.06 (±0.01) | 0.04 (±0.00) | 0.06 (±0.01) | 0.04 (±0.00) | 0.03 (±0.00) | 0.05 (±0.01) | 0.08 (±0.03) |
Amyg | 0.10 (±0.02) | 0.08 (±0.01) | 0.17 (±0.03) | 0.11 (±0.02)* | 0.13 (±0.01) | 0.24 (±0.04) | 0.14 (±0.01) | 0.18 (±0.03) |
Hypo | 0.20 (±0.01) | 0.25 (±0.01) | 0.23 (±0.02) | 0.19 (±0.02) | 0.25 (±0.03) | 0.24 (±0.02) | 0.31 (±0.03) | 0.33 (±0.02) |
MB | 0.28 (±0.03) | 0.29 (±0.02) | 0.28 (±0.04) | 0.29 (±0.04) | 0.25 (±0.01) | 0.22 (±0.01) | 0.26 (±0.01) | 0.24 (±0.01) |
5-HT | ||||||||
Experiment 4 | Experiment 5 | |||||||
Male | Female | Male | Female | |||||
Saline | AMPH | Saline | AMPH | Alone | Social Int. | Alone | Social Int. | |
Region | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) | Mean (±SEM) |
Nacc | 0.49 (±0.05) | 0.52 (±0.05) | 0.52 (±0.06) | 0.60 (±0.07) | 0.43 (±0.03) | 0.35 (±0.02) | 0.33 (±0.02) | 0.36 (±0.02) |
Str | 0.24 (±0.01) | 0.31 (±0.01) | 0.31 (±0.02) | 0.36 (±0.02) | 0.18 (±0.01) | 0.40 (±0.02)* | 0.14 (±0.01) | 0.21 (±0.02)* |
mPFC | 0.15 (±0.02) | 0.16 (±0.02) | 0.15 (±0.02) | 0.23 (±0.03) | 0.15 (±0.01) | 0.15 (±0.01) | 0.21 (±0.01) | 0.19 (±0.01) |
Amyg | 0.53 (±0.04) | 0.42 (±0.03) | 0.62 (±0.09) | 0.57 (±0.06) | 0.28 (±0.04) | 0.21 (±0.02) | 0.48 (±0.01) | 0.46 (±0.01) |
Hypo | 0.36 (±0.05) | 0.42 (±0.02) | 0.58 (±0.05) | 0.67 (±0.04) | 0.53 (±0.06) | 0.67 (±0.08) | 0.58 (±0.07) | 0.61 (±0.09) |
MB | 0.64 (±0.02) | 0.59 (±0.04) | 0.70 (±0.03) | 0.73 (±0.03) | 0.59 (±0.05) | 0.75 (±0.05) | 0.68 (±0.08) | 0.72 (±0.07) |
p<0.05 compared to same-sex control group in that region.