Table 3.
Procalcitonin diagnostic levels for sepsis in prospective studies in ICU populations
| Name | Year | Number | Ref | PCT <0.5 | 0.6 to <1.0 | 1.1 to <1.5 | 1.6 to 2.0 | Sensitivity (%) | Specificity (%) |
|---|---|---|---|---|---|---|---|---|---|
| Al-Nawas | 1996 | 337 | [32] | 0.5 | 60 | 79 | |||
| Bossink | 1999 | 200 | [33] | 0.5 | 65 | 58 | |||
| Sudhir | 2011 | 100 | [34] | 0.5 | 94 | – | |||
| Ugarte | 1999 | 205 | [35] | 0.6 | 68 | 61 | |||
| Muller | 2000 | 101 | [36] | 1.0 | 89 | 94 | |||
| Aouifi | 2000 | 97 | [37] | 1.0 | 85 | 95 | |||
| Ruokonen | 2002 | 208 | [38] | 0.8 | 68 | 48 | |||
| G-B | 2002 | 119 | [39] | 1.0 | 95 | 65 | |||
| Whang | 1998 | 29 | [40] | 1.1 | 67 | 80 | |||
| Oberhoffer | 2000 | 242 | [41] | 1.4 | 84 | 83 | |||
| Wanner | 2000 | 405 | [42] | 1.5 | 76a | 77 | |||
| Harbarth | 2001 | 78 | [9] | 1.1 | 97 | 78 | |||
| Tugrul | 2002 | 85 | [43] | 1.3 | 73 | 83 | |||
| Hensler | 2003 | 137 | [44] | 1.5 | 42a | 73 | |||
| Castelli | 2004 | 150 | [18] | 1.1 | 79 | 85 | |||
| Mokart | 2005 | 50 | [45] | 1.1 | 81 | 72 | |||
| Brunkhorst | 2000 | 185 | [46] | 2.0 | 96 | 86 | |||
| Suprin | 2000 | 101 | [47] | 2.0 | 65 | 70 | |||
| Meisner | 2002 | 208 | [48] | 2.0 | 87 | 78 | |||
| DeTalance | 2003 | 108 | [49] | 2.0 | 91 | 89 | |||
| Luzzani | 2003 | 70 | [50] | 2.0 | 76 | 84 | |||
| Du | 2003 | 51 | [51] | 1.6 | 80 | 74 | |||
| Geppert | 2003 | 55 | [52] | 2.0 | 87 | 75 | |||
| Endo | 2008 | 82 | [53] | 2.0 | 95 | 78 | |||
| Meynaar | 2011 | 76 | [54] | 2.0 | 97 | 80 |
aThese studies included trauma patients, PCT is known to rise after trauma unrelated to sepsis
ref reference