TrialID Country	Who was treated? (Age)	How long was the follow‐up?	Trialdesign? (No. of participantsa)	Was it a cluster‐RCT? (No. of clusters)	What intervention? (Dose)	Co‐interventions?b	What control?	How long was the treatment?	Endemic area? (Community category number)
Alderman 2006 (Cluster) Uganda	Children (1 to 7 years)	3 years	RCT (27,995)	Yes (48)	Albendazole (400 mg)	Child health package – both groups	No treatment	Every 6 months	Yes (2)
Awasthi 1995 (Cluster) India	Children (1 to 4 years)	2 years	Quasi‐RCT (3712)	Yes (50)	Albendazole (400 mg)	None	Placebo	Every 6 months	Yes (3)
Awasthi 2000 India	Children (1.5 to 3.5 years)	2 years	Quasi‐RCT (1045)	No	Albendazole (600 mg)	None	Placebo	Every 6 months	Yes (3)
Awasthi 2001 (Cluster) India	Children (1 to 4 years)	1.5 years	RCT (1672)	Yes (124)	Albendazole ± vitamin A (100,000 units)	Child health package – both groups	Placebo + vitamin A	Every 6 months	Yes (3)
Awasthi 2013 (Cluster) India	Children (≤ 5 years)	5 years	RCT factorial (8338)	Yes (72)	Albendazole (400 mg) ± vitamin A	Child health package – both groups	Usual care	Every 6 months	Yes (3)
Beach 1999 Haiti	Children (grades 1 to 4)	4 months	RCT (853)	No	Albendazole (400 mg) Ivermectin (200 to 400 μg/kg)	None	Placebo + vitamin C (250 mg)	Single dose	Yes (3)
Donnen 1998 Zaire	Children (0 to 72 months)	1 year	RCT (222)	No	Mebendazole (500 mg)	None	Placebo + vitamin A (60 mg) No treatment	Every 3 months	Yes (3)
Dossa 2001 Benin	Children (3 to 5 years)	10 months	RCT (65)	No	Albendazole (200 mg) ± iron	None	Placebo	Repeated 1 month later	Yes (2)
Fox 2005 Haiti	Children (5 to 11 years)	6 months	RCT (626)	No	Albendazole (400 mg) ± vitamin C (250 mg) Diethylcarbamazine (DEC, 6 mg/kg)	None	Placebo	Single dose	Yes (2)
Freij 1979a Ethiopia	Children (1.5 to 5 years)	28 days	Quasi‐RCT (13)	No	Piperazine (3 g)	Child health package – both groups	Placebo	Single dose	Infected children (unclear)
Freij 1979b Ethiopia	Children (1 to 5 years)	34 days	Quasi‐RCT (44)	No	Piperazine (3 g x 2)	None	Placebo	Single dose	Infected children (3)
Garg 2002 Kenya	Children (2 to 4 years)	6 months	RCT (347)	No	Mebendazole (500 mg)	Child health package – both groups	Placebo	Single dose	Yes (2)
Goto 2009 Bangladesh	Children (≤ 11 months)	36 weeks	RCT (410)	No	Albendazole (200 mg) ± secnidazole (0.5 mL/kg, anti‐Giardia)	None	Placebo	Every 12 weeks	Yes (2)
Greenberg 1981 Bangladesh	Children (1.5 to 8 years)	11 months	RCT (152)	No	Piperazine citrate (80 mg/kg)	None	Placebo	Two doses in 2 weeks	Yes (1)
Hadju 1996 Indonesia	Children (6 to 10 years)	7 weeks	RCT (64)	No	Pyrantel pamoate (10 mg/kg)	None	Placebo	Single dose	Yes (1)
Hadju 1997 Indonesia	Children (± 8.3 years)	1 year	RCT (330)	No	Albendazole (400 mg) Pyrantel pamoate (10 mg/kg)	None	Placebo	Single dose or every 6 months	Yes (1)
Hall 2006 (Cluster) Vietnam	Children (± 104.5 months)	2 years	RCT (2,659)	Yes (80)	Albendazole (400 mg) ± retinol (200,000 IU)	None	Placebo	Every 6 months	Yes (1)
Kirwan 2010 Nigeria	Children (1 to 5 years)	14 months	RCT (320)	No	Albendazole (200 to 400 mg)	Child health package – both groups	Placebo	Every 4 months	Yes (3)
Kloetzel 1982 Cameroon	Children (1 to 8 years)	10 months	RCT (337)	No	Mebendazole (100 mg x3)	None	Placebo	3 doses in 3 days	Yes (1)
Koroma 1996 Sierra Leone	Children (6 to 10 years)	6 months	RCT (187)	No	Albendazole (400 mg)	None	Placebo	Single dose	Yes (2)
Kruger 1996 South Africa	Children (6 to 8 years)	11 months	RCT (74)	No	Albendazole (400 mg) ± soup fortified with iron and vitamin C	Child health package – both groups	Placebo	Repeated at 4 months	Yes (3)
Kvalsvig 1991a South Africa	Children (primary school)	1 month	RCT (unclear)	No	Mebendazole (500 mg)	None	Placebo	Single dose	Infected children (1)
Lai 1995 Malaysia	Children (8 years)	2 years	RCT (314)	No	Mebendazole (100 mg) + pyrantel (200 mg)	None	Placebo	Every 3 months	Yes (1)
Le Huong 2007 Vietnam	Children	6 months	RCT factorial (510)	No	Mebendazole (500 mg)	Iron‐fortified noodles	Placebo	Twice 3 months apart	Yes (2)
Michaelsen 1985 Botswana	Children (5 to 14 years)	5 months	RCT (121)	No	Tetrachloroethylene (0.1 mL/kg)	None	Placebo	Single dose	Yes (1)
Miguel 2004 (Cluster) Kenya	Children (8 years)	2 years	RCT (9102)	Yes (65)	Albendazole (400 to 600 mg)	Child health package – only intervention group	No treatment	Every 6 months	Yes (1)
Ndibazza 2012 Uganda	Children (± 15 months)	Post‐treatment	RCT factorial (1423)	No	Albendazole (200 to 400 mg)	Child health package – both groups	Placebo	??	Yes (3)
Nga 2009 Vietnam	Children (6 to 8 years)	4 months	RCT (510)	No	Albendazole (400 mg) ± multi‐micronutrient fortified biscuit	None	Placebo	Single dose	Yes (2)
Nokes 1992 Jamaica	Children (9 to 12 years)	9 weeks	RCT (103)	No	Albendazole (400 mg x3)	None	Placebo	Single dose	Infected children (1)
Olds 1999 China, Philippines and Kenya	Children (school children)	6 months	RCT (103)	No	Albendazole (400 mg) ± praziquantel (40 mg/kg)	None	Placebo	Single dose	Yes (1)
Palupi 1997 Indonesia	Children (2 to 5 years)	9 weeks	RCT (191)	No	Albendazole (400 mg)	Iron	Iron (30 mg weekly)	Single dose	Yes (2)
Rousham 1994 (Cluster) Bangladesh	Children (2 to 6 years)	18 months	RCT (1,402)	Yes (13)	Mebendazole (500 mg) Pyrantel pamoate (10 mg/kg)	None	Placebo	Every 2 months	Yes (1)
Sarkar 2002 Bangladesh	Children (2 to 12 years)	16 weeks	RCT (81)	No	Pyrantel pamoate (11 mg/kg)	None	Placebo	Single dose	Infected children (1)
Simeon 1995 Jamaica	Children (6 to 12 years)	26 weeks	RCT (392)	No	Albendazole (800 mg)	None	Placebo	Repeated 3 to 6 months after	Infected children (1)
Solon 2003 Philippines	Children (grades 1 to 6)	16 weeks	RCT (851)	No	Albendazole (400 mg) ± multivitamin and iron	None	Placebo	Repeated 3 to 6 months after	Yes (2)
Stephenson 1989 Kenya	Children (grades 1 to 2)	6 months	RCT (150)	No	Albendazole (400 mg)	None	Placebo	Single dose	Yes (1)
Stephenson 1993 Kenya	Children (grades 1 to 5)	8 months	RCT (284)	No	Albendazole (600 mg)	None	Placebo	Repeated 3 to 6 months after	Yes (1)
Stoltzfus 1997 (Cluster) Tanzania, Zanzibar	Children (± 10.5 years)	12 months	RCT (3063)	Yes (12)	Mebendazole (500 mg, 2x or 3x)	None	Placebo	Every 4 or 6 months	Yes (1)
Stoltzfus 2001 Tanzania, Zanzibar	Children (6 to 59 months)	12 months	RCT factorial (359)	No	Mebendazole (500 mg) ± iron	None	Placebo	Every 3 months	Yes (2)
Sur 2005 India	Children (2 to 5 years)	12 months	RCT (683)	No	Albendazole (400 mg) ± vitamin B	None	Placebo	Every 6 months	Yes (2)
Tee 2013 Malaysia	Children	12 months	RCT (33)	No	Albendazole (400 mg x 2)	None	Placebo	Single dose	Yes (NA)
Watkins 1996 Guatemala	Children (7 to 12 years)	6 months	RCT (226)	No	Albendazole (400 mg)	None	Placebo	Repeated at 12 weeks	Yes (1)
Willett 1979 Tanzania	Children (6 to 91 months)	12 months	RCT (268)	No	Levamisole (2.5 mg/kg)	None	Placebo	Every 3 months	Yes (3)
Wiria 2013 (Cluster) Indonesia	Children and adults ≥ 2 years	21 months	RCT (855)	Yes (954)	Albendazole (400 mg x 3)	None	Placebo	Single dose	Yes (1)
Yap 2014 Myanmar, China	Children (9 to 12 years)	6 months	RCT (194)	No	Albendazole (400 mg x 3)	None	Placebo	Single dose	Infected children (NA)