Methods | Quasi‐RCT Length of follow‐up: 1.75 months (7 weeks) |
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Participants | All children living in endemic area Number analysed for primary outcome: 64 Age range: 6 to 10 years Inclusion criteria: boys aged 6 to 10 years attending second grade at 3 primary schools; completed assessment and provided a stool sample; randomized by descending hookworm count (all treated) Exclusion criteria: none stated |
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Interventions | Single dose vs placebo
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Outcomes |
Not included in review: egg counts arithmetic and geometric means (Kato‐Katz); weight‐for‐age (NCHS reference) |
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Notes | Location: Indonesia Community category: 1 Large drops in geometric mean egg counts in placebo noted Source of funding not reported. |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Randomized: "Randomly assigned" by descending A. lubricoides egg count" |
Allocation concealment (selection bias) | Unclear risk | No details reported. |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | "Double‐blind". Participants blinded both placebo and treatment identical round white tablets, no information about provider and assessor blinding. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | 85% (64/75) of randomized participants were evaluated. Reasons for loss to follow‐up included: moved away, refused to be examined, did not return a stool sample, absent during examination. Not clear how many lost from each treatment group. Inclusion of all randomized participants (number evaluable/number randomized): 85% (64/75). |
Selective reporting (reporting bias) | Low risk | All stated outcomes reported. |
Other bias | Low risk | No obvious other source of bias. |