Methods | RCT Length of follow‐up: 6 months |
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Participants | All children living in endemic area Number analysed for primary outcome: 187 Age range: 6 to 10 years Inclusion criteria: selected (unclear how) urban and rural school primary children aged 6 to 10 years Exclusion criteria: not stated |
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Interventions | Single dose vs placebo
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Outcomes |
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Notes | Location: Sierra Leone Community category: 2 Source of funding: Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | "Randomized", no further details provided. |
Allocation concealment (selection bias) | Unclear risk | No details reported. |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | No details reported. |
Incomplete outcome data (attrition bias) All outcomes | High risk | 76% (187/247) of randomized participants were evaluated. Reasons for loss to follow‐up not reported. Inclusion of all randomized participants (number evaluable/number randomized): 76% (187/247). |
Selective reporting (reporting bias) | Low risk | All stated outcomes reported. |
Other bias | Low risk | No obvious other sources of bias. |