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. 2015 Jul 23;2015(7):CD000371. doi: 10.1002/14651858.CD000371.pub6
Methods RCT
Length of follow‐up: 4 months (16 weeks)
Participants Infected children identified by screening
Number analysed for primary outcome: 81
Age range: 2 to 12 years
Inclusion criteria: children ages 2 to 12 living in Mirpur slum infected with Ascaris
Exclusion criteria: none stated
Interventions Single dose vs placebo
  1. Pyrantel pamoate: 11 mg/kg (Combantrin, Pfizer, Bangladesh);

  2. Placebo.

Outcomes
  1. Mean change in weight post‐treatment;

  2. Mean weight post‐treatment;

  3. Mean change in height post‐treatment;

  4. Mean height post‐treatment.


Not included in review: median % weight‐for‐age, weight‐for‐height, and height‐for‐age
Notes Location: Bangladesh
Community category: 1
Source of funding: research grant from the World Bank and was funded by the Bangladesh National Nutrition Council.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk "Random table".
Allocation concealment (selection bias) Unclear risk No details reported.
Blinding (performance bias and detection bias) All outcomes Low risk "Double‐blind"; "The syrups were identical in appearance and flavor and were packaged in identical containers. Randomized patient numbers were labeled on the bottles to maintain the double blind design".
Incomplete outcome data (attrition bias) All outcomes Low risk 94% (81/85) of randomized participants were evaluated. Inclusion of all randomized participants (number evaluable/number randomized): 94% (81/85).
Selective reporting (reporting bias) Low risk Pre‐specfied outcomes reported.
Other bias Low risk No obvious other source of bias.