Solon 2003

Methods	RCT Length of follow‐up: 16 weeks
Participants	All children living in endemic area Number analysed for primary outcome: 808/851 Age range/ mean age: 10 years Inclusion criteria: Children in grades 1 to 6 Exclusion criteria: Children with Haemoglobin < 8 g/dL
Interventions	Single dose vs placebo Fortified beverage (multivitamin and iron) twice per day for 16 weeks with anthelmintic therapy (Albendazole 400 mg); Fortified beverage with placebo anthelmintic therapy; Non‐fortified beverage with anthelmintic therapy (400 mg); Non‐fortified beverage with placebo anthelmintic therapy.
Outcomes	No useable data Not included in review: urine iodine, stool egg count. Measured but not reported: weight, height, haemoglobin, physical fitness (Harvard step test), heart rate, cognitive ability measured by the Primary Mental Abilities Test for Filipino Children. The test measures verbal, non verbal and quantitative skills.
Notes	Location: Philippines Community category: 2 Narrative results: No significant difference in change in weight. Deworming improved the iron status of a subgroup of moderately to severely subjects. Deworming had either no effect or a negative effect on fitness scores, and the effect on heart rate was inconclusive. Deworming had either no effect or a negative effect on mental ability scores. Sources of support: The Nutrition Center of the Philippines, The Procter & Gamble Co.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Randomization at individual level, no further details.
Allocation concealment (selection bias)	Unclear risk	No details reported.
Blinding (performance bias and detection bias) All outcomes	Low risk	Double‐blind trial. "Both the researchers and the trial participants were blinded to the treatment assignment of each child". "Placebo beverage and placebo anthelmintic pills were indistinguishable from their counterparts in appearance, smell and taste".
Incomplete outcome data (attrition bias) All outcomes	Low risk	808/851 (95%) enrolled participants were evaluated, no reasons for withdrawal reported. Inclusion of all randomized participants (number evaluable/number randomized): 95% (808/851).
Selective reporting (reporting bias)	High risk	Nutritional and haemoglobin outcomes not fully reported.
Other bias	Low risk	No obvious other source of bias.