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. 2015 Jul 23;2015(7):CD000371. doi: 10.1002/14651858.CD000371.pub6
Methods RCT
Length of follow‐up: 12 months
Participants Infected children identified by screening
Mean age: 7.3 years
Number analysed for primary outcome: 33
Inclusion criteria: children with confirmed Trichus trichiura in a rural school
Exclusion criteria: none reported
Interventions Single dose vs placebo
  1. Albendazole: 2 x 400 mg doses on 2 consecutive days;

  2. Placebo.

Outcomes
  1. Mean change in height;

  2. Median change in weight;

  3. Weight‐for‐age z‐score;

  4. Height‐forage z‐score;

  5. Weight‐for‐height z‐score.


Not included in review: urinary TNF‐alpha levels
Notes Location: Sekolah Rendah Kebangsaan Tawang, Kelantan, Malaysia
Community category: NA
Source of funding: Universiti Sains Malaysia Short Term Grant.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Randomization software was used.
Allocation concealment (selection bias) Unclear risk No details reported.
Blinding (performance bias and detection bias) All outcomes Unclear risk For participants and assessors, no details were reported. "
Both the active drug and placebo were repackaged by a pharmacist blinded to the trial groups".
Incomplete outcome data (attrition bias) All outcomes Low risk 33/37 participants analysed for the primary outcome; reasons for loss to follow‐up unclear.
Inclusion of all randomized participants (number evaluable/number randomized): 89% (33/37).
Selective reporting (reporting bias) Low risk All stated outcomes reported.
Other bias Low risk No obvious other source of bias.