Methods | RCT Length of follow‐up: 12 months |
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Participants | Infected children identified by screening Mean age: 7.3 years Number analysed for primary outcome: 33 Inclusion criteria: children with confirmed Trichus trichiura in a rural school Exclusion criteria: none reported |
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Interventions | Single dose vs placebo
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Outcomes |
Not included in review: urinary TNF‐alpha levels |
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Notes | Location: Sekolah Rendah Kebangsaan Tawang, Kelantan, Malaysia Community category: NA Source of funding: Universiti Sains Malaysia Short Term Grant. |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Randomization software was used. |
Allocation concealment (selection bias) | Unclear risk | No details reported. |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | For participants and assessors, no details were reported. " Both the active drug and placebo were repackaged by a pharmacist blinded to the trial groups". |
Incomplete outcome data (attrition bias) All outcomes | Low risk | 33/37 participants analysed for the primary outcome; reasons for loss to follow‐up unclear. Inclusion of all randomized participants (number evaluable/number randomized): 89% (33/37). |
Selective reporting (reporting bias) | Low risk | All stated outcomes reported. |
Other bias | Low risk | No obvious other source of bias. |