Methods | RCTRCT Length of follow‐up: 6 months |
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Participants | Infected children identified by screening Number analysed for primary outcome: 194 Age range: 9 to 12 years Inclusion criteria: children aged 9 to 12 years from 5 primary schools, with at least one type of STH infection. Exclusion criteria: deworming treatment within 6 months before the current trial. |
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Interventions | Single dose vs placebo
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Outcomes |
Not included in review: parasitological examination. |
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Notes | Location: Bulanghsam township bordering Myanmar, a sub‐division of Menghai county in Xishuangbanna Dai autonomous prefecture, situated in Yunnan province, P.R. China Community category: N/A Source of funding: Swiss Tropical and Public Health Institute in Basel, Switzerland and the National Institute of Parasitic Diseases, Chinese Center of Diseases Control and Prevention in Shanghai, P.R. China. |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | "The treatment allocation sequence was generated by a statistician using block randomization with randomly varying block sizes of 2, 4, and 6." |
Allocation concealment (selection bias) | Low risk | "Albendazole and placebo tablets were packaged by staff not involved in the field work into sealed envelopes marked with unique identifiers." |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | Participants and personnel blinded. Not reported whether the assessors for height and weight were blinded. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Inclusion of all randomized participants (number evaluable/number randomized): 92% (194/211). |
Selective reporting (reporting bias) | Low risk | All stated outcomes reported. |
Other bias | Low risk | No other obvious risk of bias. |
CI: confidence interval; Community category: a measure of the prevalence and intensity of infection (see Table 11); NCHS: National Center for Health Statistics; SD: standard deviation; SEM: standard error of the mean.