Alam 2006

Trial name or title	Relative efficacy of two regimens of ante‐helminthic treatment
Methods	Clinical trial
Participants	Total enrolment: 200 Inclusion criteria: age 2 to 5 years; not suffering from serious chronic illness; stool test positive for STHs; not taken any anthelminthic drug in previous 6 months; parents/guardian agree their child's participation Exclusion criteria: age < 2 years and > 5 years; stool test negative for any intestinal helminth; suffering from serious chronic illness; parents/guardian not willing to give consent for their child's participation; if he/she receives any anthelminthic drug after survey but before the trial interventions
Interventions	Conventional treatment of 400 mg of albendazole in a single dose at 6‐month interval; Intervention group: 400 mg of albendazole in a single‐dose treatment at 3‐month interval.
Outcomes	Primary To determine the relative efficacy of de‐worming at every 3 months vs every 6 month single dose of albendazole treatment. Secondary To compare additional morbidity information such as diarrhoeal diseases, respiratory tract infections, nutritional status and E. histolytica associated morbidity between 2 groups.
Starting date	Not yet recruiting
Contact information	Mohammad M Alam MBBS, Principal Investigator, ICDDR,B: Centre for Health and Population Research, masud_icddrb@yahoo.com
Notes	ClinicalTrials.gov identifier: NCT00367627 Sources of support: International Centre for Diarrhoeal Disease Research, Bangladesh (sponsor)