Table 1. Number and degree of fusion after different treatments.
DOFa | Number of palatal shelves at different position | |||||||
---|---|---|---|---|---|---|---|---|
24 hrs after infection (n = 15) | 48 hrs after infection (n = 8) | |||||||
shLuc | shIrf6 | TGFβ3 | shIrf6 + TGFβ3 | shLuc | shIrf6 | TGFβ3 | shIrf6 + TGFβ3 | |
Anterior | ||||||||
0–25% | 15 | 15 | 0 | 12 | 0 | 0 | 0 | 0 |
25–50% | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 |
50–75% | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 |
75–100% | 0 | 0 | 13 | 0 | 8 | 8 | 8 | 8 |
Middle | ||||||||
0–25% | 13 | 13 | 0 | 12 | 0 | 0 | 0 | 0 |
25–50% | 2 | 2 | 0 | 3 | 0 | 0 | 0 | 0 |
50–75% | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 1 |
75–100% | 0 | 0 | 13 | 0 | 8 | 8 | 8 | 7 |
Posterior | ||||||||
0–25% | 13 | 15 | 0 | 13 | 0 | 0 | 0 | 0 |
25–50% | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
50–75% | 0 | 0 | 4 | 1 | 0 | 0 | 0 | 0 |
75–100% | 0 | 0 | 11 | 0 | 8 | 8 | 8 | 8 |
Average of DOF | 9.3 ± 8.1% | 9.0 ± 7.3% | 84.9 ± 9.8% | 16.3 ± 10.2%* | 90.4 ± 5.3% | 89.2 ± 5.0% | 91 ± 5.2% | 88.8 ± 5.2% |
aDOF, Degree of fusion.
*Significant difference between TGFβ3 and shIrf6 + TGFβ3 at 24 hrs after infection was analyzed by t-test (p < 0.001).