Table 2.

Selected cost parameters used in the model (greater detail and full list provided in Additional files 5 and 4)

Variable name	Variable definition	Source, derivation and application	Expected value and 95 % uncertainty interval
Incremental CCC cost from diagnosis to surgery	Incremental cost of CCC programme from provisional diagnosis to surgery (difference in costs for pathway of care with CCC minus pathway of care in business-as-usual comparator)	Consultation with local health care professionals (costed based on average salaries + 50 % overheads)	$64.03 per patient
			($29.42 to $98.64)
			Normal distribution
		See Additional file 5
Incremental CCC cost from surgery to start of chemotherapy	Incremental cost of CCC programme from surgery to start of chemotherapy	Consultation with local health care professionals (costed based on average salaries + 50 % overheads)	$5.00 per patient
			($-10.39 to $20.39)
			Normal distribution
		See Additional file 5
Cost of chemotherapy per patient	Cost per patient of 12 cycles of chemotherapy with oxaliplatin over 6 months	Bottom-up costing approach including cost of pharmaceuticals, outpatient attendance and overheads.	$17,811.78 per patient ($14,494.69 to $21,390.41)
			Gamma distribution
		See Additional file 4
Dietician costs	Additional costs from dietician referrals precipitated by a CCC	Expert estimates	$115.89 per patient ($81.38 to $141.16)
		Referrals estimated to increase by 50 %, 2 contacts per referral. See Additional files 5 and 4	Gamma distribution
Social worker costs	Additional costs from social worker referrals precipitated by a CCC	Referrals estimated to increase by 42 %, 6 contacts per referral.	$327.95 to $483.97
		See Additional files 5 and 4	Gamma distribution