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. 2015 May 26;10:16. doi: 10.1186/s13027-015-0011-3

Table 4.

Risk factors and association with a histological diagnosis of CIN 1 or worse

Risk factor OR (95%CI) p-value
Age
<35 years 1.19 (0.59-2.40) 0.3
≥35 years
Initiation of sexual activity
<16 years 2.2 (0.94-5.08) 0.03
≥16 years
Number of partners
1 0.7 (0.36-1.54) 0.2
≥2
Number of partners
<3 1.21 (0.5-2.95) 0.6
≥3
Pregnancies
None 0.46 (0.18-1.77) 0.06
≥1
Oral contraceptive use
Yes 1.2 (0.5-2.62) 0.3
No
Smoking
Yes 0.6 (0.28-1.22) 0.11
No
HPV infectiona
Yes 2.76 (1.05-7.19) 0.03
No
HPV 16 and 18 infection
Yes
No 3.53(1.17-10.67) 0.02
Infection by HPV types other than HPV 16 and 18
Yes
No 2.25(0.80-6.36) 0.08

aReference HPV-negative, CIN: Cervical intraepithelial neoplasia