TABLE 5.
Diversity and divergence of GenBank sequences for select HSV-2 open reading frames
| ORF | Protein | GenBank |
New sequences |
||||||
|---|---|---|---|---|---|---|---|---|---|
| No. of sequences | Parametera | % Diversity/divergencea (SE) |
No. of sequences | Parametera | % Diversity/divergencea (SE) |
||||
| Nucleotide | Amino acid | Nucleotide | Amino acid | ||||||
| UL23 | Thymidine kinase | 185 | Diversity | 0.2 (0.1) | 0.4 (0.2) | 34 | Diversity | 0.2 (0.1) | 0.3 (0.1) |
| Divergence from HG52 RefSeq | 0.1 (0.1) | 0.3 (0.2) | Divergence from HG52 RefSeq | 0.2 (0.1) | 0.5 (0.3) | ||||
| Divergence from HG52 ILMN | 0.1 (0.1) | 0.3 (0.2) | Divergence from HG52 ILMN | 0.2 (0.1) | 0.5 (0.3) | ||||
| Divergence from SD90e | 0.2 (0.1) | 0.3 (0.1) | Divergence from SD90e | 0.2 (0.1) | 0.2 (0.1) | ||||
| UL27 | Virion membrane glycoprotein B | 108 | Diversity | 0.2 (0.0) | 0.4 (0.1) | 34 | Diversity | 0.2 (0.0) | 0.5 (0.1) |
| Divergence from HG52 RefSeq | 0.2 (0.1) | 0.4 (0.1) | Divergence from HG52 RefSeq | 0.2 (0.1) | 0.4 (0.1) | ||||
| Divergence from HG52 ILMN | 0.2 (0.0) | 0.3 (0.1) | Divergence from HG52 ILMN | 0.2 (0.0) | 0.4 (0.1) | ||||
| Divergence from SD90e | 0.2 (0.1) | 0.4 (0.1) | Divergence from SD90e | 0.2 (0.1) | 0.5 (0.2) | ||||
| UL30 | DNA polymerase catalytic subunit | 54 | Diversity | 0.1 (0.0) | 0.2 (0.1) | 34 | Diversity | 0.1 (0.0) | 0.1 (0.0) |
| Divergence from HG52 RefSeq | 0.1 (0.0) | 0.3 (0.1) | Divergence from HG52 RefSeq | 0.1 (0.1) | 0.3 (0.1) | ||||
| Divergence from HG52 ILMN | 0.1 (0.0) | 0.3 (0.1) | Divergence from HG52 ILMN | 0.1 (0.0) | 0.3 (0.1) | ||||
| Divergence from SD90e | 0.1 (0.0) | 0.2 (0.1) | Divergence from SD90e | 0.1 (0.0) | 0.2 (0.1) | ||||
| UL49 | Tegument protein | 122 | Diversity | 0.8 (0.2) | 0.9 (0.3) | 34 | Diversity | 0.5 (0.1) | 0.8 (0.3) |
| Divergence from HG52 RefSeq | 0.6 (0.2) | 0.7 (0.3) | Divergence from HG52 RefSeq | 0.5 (0.1) | 0.7 (0.3) | ||||
| Divergence from HG52 ILMN | 0.6 (0.2) | 0.7 (0.3) | Divergence from HG52 ILMN | 0.7 (0.2) | 0.7 (0.3) | ||||
| Divergence from SD90e | 0.9 (0.2) | 1.5 (0.6) | Divergence from SD90e | 0.8 (0.2) | 1.1 (0.4) | ||||
| US4 | Virion membrane glycoprotein G | 141 | Diversity | 0.4 (0.1) | 0.7 (0.1) | 34 | Diversity | 0.4 (0.1) | 0.7 (0.1) |
| Divergence from HG52 RefSeq | 0.4 (0.1) | 0.7 (0.2) | Divergence from HG52 RefSeq | 0.4 (0.1) | 0.7 (0.2) | ||||
| Divergence from HG52 ILMN | 0.4 (0.1) | 0.7 (0.2) | Divergence from HG52 ILMN | 0.4 (0.1) | 0.6 (0.2) | ||||
| Divergence from SD90e | 0.5 (0.1) | 0.8 (0.2) | Divergence from SD90e | 0.4 (0.1) | 0.7 (0.2) | ||||
| US7 | Virion membrane glycoprotein I | 49 | Diversity | 0.3 (0.1) | 0.6 (0.3) | 34 | Diversity | 0.3 (0.1) | 0.6 (0.2) |
| Divergence from HG52 RefSeq | 0.3 (0.1) | 0.6 (0.3) | Divergence from HG52 RefSeq | 0.4 (0.1) | 0.7 (0.3) | ||||
| Divergence from HG52 ILMN | 0.3 (0.1) | 0.6 (0.3) | Divergence from HG52 ILMN | 0.3 (0.1) | 0.7 (0.3) | ||||
| Divergence from SD90e | 0.3 (0.1) | 0.6 (0.3) | Divergence from SD90e | 0.3 (0.1) | 0.5 (0.3) | ||||
| US8 | Virion membrane glycoprotein E | 50 | Diversity | 0.2 (0.0) | 0.4 (0.1) | 34 | Diversity | 0.2 (0.0) | 0.4 (0.1) |
| Divergence from HG52 RefSeq | 0.2 (0.1) | 0.6 (0.3) | Divergence from HG52 RefSeq | 0.2 (0.1) | 0.6 (0.2) | ||||
| Divergence from HG52 ILMN | 0.1 (0.0) | 0.2 (0.1) | Divergence from HG52 ILMN | 0.2 (0.1) | 0.4 (0.2) | ||||
| Divergence from SD90e | 0.1 (0.1) | 0.3 (0.2) | Divergence from SD90e | 0.2 (0.1) | 0.3 (0.2) | ||||
a
GenBank accession numbers: HG52 RefSeq, NC_001798.1; HG52 ILMN, JN561323; SD90e, KF781518.