Table 5.
Parametera | Serum P levels (ng/ml), day 3 ETb | ||
---|---|---|---|
<1.0 | 1.0-1.49 | ≥1.5 | |
No. of fresh cycles | 7627 | 2373 | 846 |
Female age (years) | 31.1 ± 5.1 | 31.8 ± 5.0* | 32.1 ± 5.1 |
BMI (kg/m2) | 22.7 ± 3.2 | 22.3 ± 3.0* | 22.1 ± 3.0 |
Basal FSH (IU/L) | 7.7 ± 2.9 | 7.3 ± 2.4* | 7.2 ± 2.2 |
Total dose of Gn (IU) | 2201.2 ± 940.7 | 2268.6 ± 879.3* | 2357.1 ± 890.1* |
Serum E2 (pg/ml), hCG day | 3941.8 ± 2118.6 | 5321.0 ± 2353.8* | 6201.8 ± 4598.0* |
Serum LH (IU/L), hCG day | 2.0 ± 1.3 | 1.9 ± 1.4 | 1.72 ± 1.9* |
Endometrial thickness (mm), hCG day | 12.3 ± 2.4 | 12.2 ± 2.5 | 12.0 ± 2.4* |
No. of oocytes retrieved | 9.3 ± 4.4 | 11.1 ± 4.6* | 12.0 ± 4.8* |
No. of 2PN oocytes | 6.4 ± 3.3 | 7.5 ± 3.5* | 7.8 ± 4.8 |
No. of 2PN cleavage embryos | 6.4 ± 3.3 | 7.5 ± 3.5* | 7.8 ± 4.8 |
No. of available embryos | 5.0 ± 2.8 | 5.7 ± 3.0* | 5.9 ± 3.2 |
Fertilization rate (%) | 69 | 67.4* | 65.1* |
Cleavage rate (%) | 97.8 | 97.7 | 97.3** |
No. of transferred embryos | 2.10 ± 0.34 | 2.12 ± 0.34* | 2.14 ± 0.39 |
No. of transferred top-quality embryos | 1.97 ± 0.55 | 2.00 ± 0.53** | 2.02 ± 0.56* |
Implantation rate (%) | 36.3 | 31.6* | 26* |
CPR (%) | 50.4 | 45.5* | 36.2* |
Note: Day 3 ET subgroups according progesterone cut-off levels: <1 ng/ml, 1–1.49 ng/ml, and ≥1.5 ng/ml. P = progesterone
aAll values are presented as the mean ± SD or count (%)
bDifferences between subgroups were determined using ANOVA followed by the LSD-t test or the Kruskal-Wallis (KW) test and subsequent pairwise multiple comparisons for continuous variables and the chi-square test or Fisher’s exact test for categorical variables
*p < 0.01 compared with the previous subgroup
**p < 0.05 compared with the previous subgroup